BACKGROUND: In critical care patients, reaching optimal β-lactam concentrations poses challenges, as infections are caused more often by microorganisms associated with higher MICs, and critically ill patients typically have an unpredictable pharmacokinetic/pharmacodynamic profile. Conventional intermittent …

BACKGROUND: Hemodynamic assessment of critically ill patients is a challenging endeavor, and advanced monitoring techniques are often required to guide treatment choices. Given the technical complexity and occasional unavailability of these techniques, estimation of cardiac function based on clinical …

The current healthcare delivery system is under pressure. With an aging population and changing lifestyles, the incidence and prevalence of chronic diseases have grown steadily worldwide. It is presumed that people with multiple chronic diseases account for a very large proportion of healthcare utilization …

Background: Cardiac output measurements may inform diagnosis and provide guidance of therapeutic interventions in patients with hemodynamic instability. The FloTrac™ algorithm uses uncalibrated arterial pressure waveform analysis to estimate cardiac output. Recently, a new version of the algorithm has …

PURPOSE: Clinical examination is often the first step to diagnose shock and estimate cardiac index. In the Simple Intensive Care Studies-I, we assessed the association and diagnostic performance of clinical signs for estimation of cardiac index in critically ill patients. METHODS: In this prospective, …

Background One way to achieve universal health coverage (UHC) in low- and middle-income countries (LMIC) is the implementation of health insurance schemes. A robust and up to date overview of empirical evidence assessing and substantiating health equity impact of health insurance schemes among specific …

Occasion – The Hanze University and Diponegoro University started a collaboration in 2015, focusing on community health centre ‘Pudak Payung’. It became clear that there is a need for knowledge and experience, relating to health promotion, which focuses on non-communicable diseases (NCD’s) in the community …

In this paper, I propose an affective-formalist reading of what I call the affective affordances of disability; the way in which the representation of disability is able to move us. Through a comparative reading of two artworks, Michelangelo's David and Berlinde de Bruyckere's Into One-another Ill, to …

Collaborative learning tasks may represent an effective way to stimulate higher-order processes among high-ability students in regular classrooms. This study investigated the effects of task structure and group composition on the elaboration and metacognitive activities of 11th grade preuniversity students …