Clinical outcomes in ROS1-fusion positive (ROS1+) non-small cell lung cancer (NSCLC) by fusion partner and resistance mechanisms are limited. This cohort study included 56 ROS1+ patients (FISH or NGS confirmed); fusion partners were identified in 27 cases, including CD74 (n = 10), EZR (n = 7), and SDC4 …

Background The ROS1 G2032R mutation is the most common on-target resistance mutation in crizotinib treated ROS1-positive lung cancer patients. The aim of our study was to investigate resistance mechanisms in SCL34A2-ROS1G2032R positive Ba/F3 cells against second line treatment with lorlatinib. Methods …

Deze inventarisatie is uitgevoerd om inzicht te geven in de ontwikkelingen van het excellentieonderwijs in het Hoger Beroepsonderwijs (HBO). Doel is in beeld te krijgen hoe het excellentieonderwijs in het Nederlandse HBO er voor staat en wat mogelijke knelpunten en succesfactoren zijn. Nevendoelen zijn …

The overall question of this study is: to what extent do connections exist between mission statements, performance indicators, and program assessments that might indicate a significant alignment and indicate the effectiveness of honors programs?

The importance of international conferences in promoting excellence in honors education

This presentation compares the two main gifted education programmes for undergraduate students in the Netherlands and Germany. The programmes were evaluated and will be compared in terms of the institutions involved, the educational objectives pursued, the nature of support provided to the students, …