The illegal production of synthetic drugs in clandestine laboratories is an emerging threat within the European Union, necessitating improved methods for law enforcement agencies to locate these illegal sites. Combining gas chromatography and ion mobility spectrometry is a promising technology for reliably …

Insulin sensitivity and metabolic flexibility decrease in response to bed rest, but the temporal and causal adaptations in human skeletal muscle metabolism are not fully defined. Here, we use an integrative approach to assess human skeletal muscle metabolism during bed rest and provide a multi-system …

Studenten van de opleiding bouwkunde van Hogeschool Rotterdam hebben – in opdracht van verschillende woningcorporaties in de regio Rotterdam en gemeente Rotterdam – diverse vraagstukken in het kader van de veranderende energietransitie onderzocht. Dit hebben zij uitgevoerd in het atelier “De acht van …

Aims Genetic hypertrophic cardiomyopathy (HCM) is caused by mutations in sarcomere protein-encoding genes (i.e. genotype-positive HCM). In an increasing number of patients, HCM occurs in the absence of a mutation (i.e. genotype-negative HCM). Mitochondrial dysfunction is thought to be a key driver of …

The municipality of The Hague has been a member of the WHO's Global Network for Age-Friendly Cities and Communities since 2015. The municipality commissioned a survey to investigate how older citizens view the age-friendliness of their city. A cross-sectional survey was conducted among a diverse sample …

Skeletal muscle-related symptoms are common in both acute coronavirus disease (Covid)-19 and post-acute sequelae of Covid-19 (PASC). In this narrative review, we discuss cellular and molecular pathways that are affected and consider these in regard to skeletal muscle involvement in other conditions, …

This article examines whether calls for European ‘strategic autonomy’ in response to Trump’s rhetoric are qualitatively different from earlier disagreements in US-EU relations. By doing so, it re-assesses Geir Lundestad’s concept of “Empire by Invitation” to illustrate constraints for the development …

De Nederlands maatschappij is op het moment in beweging. Op deze manier ontstaat er steeds meer een gedecentraliseerde samenleving. Dit zorgt voor allerlei veranderingen, ook in de sociale sector. Om adequaat op deze veranderingen te reageren, heeft de Verkenningscommissie Hoger Sociaal Agogisch Onderwijs …

handbal is een sport waarbij veel blessures voorkomen. Als gevolg hierop zijn sporters vaak uitgeschakeld voor trainings- en wedstrijdmomenten. Dit kan resulteren in wel of geen kampioenschap. Vanuit handbalvereniging BFC (HV BFC) uit Beek is de vraag ontstaan om meer aan preventie te gaan doen. Uit …