The architecture of TP 53 , the most frequently mutated gene in human cancer, is more complex than previously thought. Using TP 53 variants as clinical biomarkers to predict response to treatment or patient outcome requires an unequivocal and standardized procedure toward a definitive strategy for the …

When treating cancer by radiation therapy it is always the goal to irradiate the tumour as much as possible and to spare the healthy tissue around it. For this a new type of radiation therapy called Volumetric Modulated ARC Therapy (VMAT) has been developed. During VMAT treatment the radiation machine …

Bioelectrical impedance analysis (BIA) may be used to assess fat free mass (FFM) with reasonable validity based on mean-level comparisons, but differences between BIA and DXA may vary by about 4 kg in an individual patient. These results require confirmation in a larger sample of HNC (Head and neck cancer) …

Posterpresentatie gehouden tijdens en in het kader van Clinical Nutrition Week 2014.

Quality of life (QoL) of cancer patients after treatment may not only be affected by the treatment itself, but also by non-treatment related factors such as co-morbidity. As co-morbidity among prostate cancer patients is prevalent it is relevant to understand its impact on QoL. In this reagard, a comparison …

Prostate cancer (PCA) has the highest prevalence for men in the western world. Besides general symptoms, these patients experience specific problems like erectyle dysfunction and urinary incontinence, which occur after treatment and may result in feelings of distress. PCA patients express a need for …

OBJECTIVE: This paper describes the development of a physical training programme for cancer patients. Four related but conceptually and empirically distinct physical problems are described: decreased aerobic capacity, decreased muscle strength, fatigue and impaired role physical functioning. The study …

Bijna alle mensen met een amputatie hebben in meer of mindere mate last van fantoomverschijnselen. Deze verschijnselen kunnen het dagelijks leven van deze patiënten behoorlijk beïnvloeden. Ondanks het feit dat fantoompijn vaak voorkomt na een amputatie, wordt toch maar een kleine groep patiënten voor …