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The Timed Swallowing Proficiency for Eating and Drinking (SPEAD) Test: Development and Initial Validation of an Instrument to Objectify (Impaired) Swallowing Capacity in Head and Neck Cancer Patients

Karsten, R. T.; Hilgers, F. J. M.; van der Molen, L.; van Sluis, K.; Smeele, L. E.; Stuiver, M. M. (Lectoraat Functioneel Herstel Bij Kanker)

Objective swallowing outcomes measure the physical swallowing function, while subjective outcomes measure swallowing perception. A test for swallowing capacity, measuring the ingestion of all consistencies is currently not available. Therefore, the Swallowing Proficiency for Eating And Drinking (SPEAD) …

2021-12AlgemeenArtikel

Characterization of automatic treatment planning approaches in radiotherapy

Geert Wortel; Dave Eekhout; Emmy Lamers (Lid Lectoraat); René van der Bel; Karen Kiers; Terry Wiersma; Tomas Janssen; Eugene Damen

Background and purpose: Automatic approaches are widely implemented to automate dose optimization in radiotherapy treatment planning. This study systematically investigates how to configure automatic planning in order to create the best possible plans. Materials and methods: Automatic plans were generated …

2021-07-13GezondheidArtikel

Self-completion of the patient-generated subjective global assessment short form is feasible and is associated with increased awareness on malnutrition risk in patients with head and neck cancer

Jager-Wittenaar, Harriët (Malnutrition And Healthy Ageing); de Bats, Hester; Welink-Lamberts, Bertine; Gort-van Dijk, Dorienke; van der Laan, Bernard; Ottery, Faith D.; Roodenburg, Jan

BACKGROUND: We aimed to assess feasibility of self-completion of the Patient-Generated Subjective Global Assessment Short Form (PG-SGA SF) by head and neck cancer patients, and to assess self-reported increased awareness regarding malnutrition risk after self-completion. METHODS: Participants were randomized …

2020-04AlgemeenArtikel

Nutrition status and health-related quality of life among outpatients with advanced head and neck cancer

Mulasi, Urvashi; Vock, D.M.; Jager-Wittenaar, Harriët (Malnutrition And Healthy Ageing); Teigen, L.; Kuchnia, A.J.; Jha, G.; Fujioka, N.; Rudrapatna, V.; Patel, M.R.; Earthman, Carrie

This pilot study evaluated nutrition status and health-related quality of life (HRQOL) outcomes among outpatients with head and neck cancer (HNC). Data were collected from 19 patients (18 males, 1 female) during 3 time points: once before chemoradiotherapy (CRT) initiation and 1 and 3 months after CRT. …

2020-03AlgemeenArtikel

Low muscle mass is associated with early termination of chemotherapy related to toxicity in patients with head and neck cancer

Sealy, Martine J. (Healthy Ageing, Allied Health Care And Nursing); Dechaphunkul, Tanadech; van der Schans, Cees P. (Healthy Ageing, Allied Health Care And Nursing); Krijnen, Wim P (Statistical Techniques For Applied Research); Roodenburg, Jan L. N.; Walker, John; Jager-Wittenaar, Harriët (Malnutrition And Healthy Ageing); Baracos, Vickie E.

BACKGROUND & AIMS: We studied whether low pre-treatment muscle mass, measured with CT at thoracic (T4) or lumbar level (L3) associates with early termination of chemotherapy related to toxicity in head and neck cancer (HNC) patients. METHODS: This was a retrospective chart and image review. Adult HNC …

2020-02AlgemeenArtikel

Het verschil in voorspelde kwaliteit van leven tussen een organ-at-risk-geoptimaliseerde planning en kwaliteit-van-leven-geoptimaliseerde planning

Willeke Fokkens (Student); Juliet Oeseburg (Student); Wouter Schaake (Begeleider); H. Erenstein (Begeleider)

Dit praktijkgericht onderzoek heeft als doel om de huidige manier van optimaliseren, organ-at-risk-geoptimaliseerde planningsmethode, te vergelijken met een nieuwe methode; kwaliteit-van-leven-geoptimaliseerde planningsmethode. Op basis van deze pilotstudie kan worden gezegd dat plannen met de kwaliteit-van-leven-geoptimaliseerde …

2020-01-13GezondheidBachelor

Translating Evidence-Based Guidelines into Practice-Are We Getting It Right? A Multi-Centre Prospective International Audit of Nutrition Care in Patients with Foregut Tumors (INFORM)

M Findlay; J. Bauer; R Dhaliwal; Marian de van der Schueren; A. Laviano; A Widaman; L Martin; AG Day; L. Gramlich

Malnutrition is highly prevalent in patients with foregut tumors comprising head and neck (HNC) and esophageal (EC) cancers, negatively impacting outcomes. International evidence-based guidelines (EBGs) for nutrition care exist; however, translation of research evidence into practice commonly presents …

2020AlgemeenArtikel

Fish oil supplementation and maintaining muscle mass in chronic disease: state of the evidence

Barbara van der Meij; V. Mazurak

Purpose of review Providing eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), in the form of fish oils, to benefit muscle is an emerging area of interest. The aim of this work was to evaluate the current literature that has assessed muscle mass as an outcome during a fish oil intervention in …

2020AlgemeenArtikel

Long-term swallowing, trismus, and speech outcomes after combined chemoradiotherapy and preventive rehabilitation for head and neck cancer; 10-year plus update

Karsten, Rebecca T.; van der Molen, Lisette; Hamming-Vrieze, Olga; van Son, RobJ. J. J. H.; Hilgers, Frans J. M.; van den Brekel, Michiel W. M.; Stuiver, Martijn M (Centre Of Expertise Urban Vitality); Smeele, Ludi E.

BACKGROUND: The objective of this study was to explore the 10-year plus outcomes of Intensity Modulated Radiotherapy with concomitant chemotherapy (CRT) combined with preventive swallowing rehabilitation (CRT+) for head and neck cancer (HNC). METHODS: Subjective and objective swallowing, trismus, and …

2020AlgemeenArtikel

Study protocol of a prospective multicenter study comparing (cost-)effectiveness of a tailored interdisciplinary head and neck rehabilitation program to usual supportive care for patients treated with concomitant chemo- or bioradiotherapy

Beck, Ann-Jean C C; Passchier, Ellen; Retèl, Valesca P; Stuiver, Martijn M (Centre Of Expertise Urban Vitality); van der Molen, Lisette; Klop, Willem M C; Navran, Arash; van Harten, Wim H; van den Brekel, Michiel W M

BACKGROUND: Since 2011, a tailored, interdisciplinary head and neck rehabilitation (IHNR) program, covered by the basic healthcare insurance, is offered to advanced head and neck cancer (HNC) patients in the Netherlands Cancer Institute (NKI). This program is developed to preserve or restore patients' …

2019-07-03AlgemeenArtikel

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