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Studying Telmisartan Plasma Exposure, Kidney Distribution, Receptor Occupancy, and Response in Patients With Type 2 Diabetes Using [11C]Telmisartan

van der Hoek, Sjoukje; Mulder, Douwe J.; T.M. Willemsen, Antoon; Visser, Ton J.; Heeres, André (Biobased Chemistry & Refinery); Slart, Riemer H.J.A.; Elsinga, Philip H.; Heerspink, Hiddo J. L.; Stevens, Jasper

The angiotensin receptor blocker telmisartan slows progression of kidney disease in patients with type 2 diabetes (T2D), yet many patients remain at high risk for progressive kidney function loss. The underlying mechanisms for this response variation might be attributed to differences in angiotensin-1 …

2022-09-07AlgemeenArtikel

Comparing lab and field agility kinematics in young football girls

DiPaolo, Stefano; Nijmeijer, Eline M; Bragonzoni, Laura; Dingshoff, Evelien; Gokeler, Alli; Benjaminse, Anne

Modifiable (biomechanical and neuromuscular) anterior cruciate ligament (ACL) injury risk factors have been identified in laboratory settings. These risk factors were subsequently used in ACL injury prevention measures. Due to the lack of ecological validity, the use of on-field data in the ACL injury …

2022-05-03AlgemeenArtikel

Evaluation of a Fully Automatic Deep Learning-Based Method for the Measurement of Psoas Muscle Area

Van Erck, Dennis; Moeskops, Pim; Schoufour, Josje D. (Lectoraat Voeding En Beweging); Weijs, Peter J. M. (Lectoraat Voeding En Beweging); Scholte Op Reimer, Wilma J. M.; Van Mourik, Martijn S.; Janmaat, Yvonne C.; Planken, R. Nils; Vis, Marije; Baan, Jan; Hemke, Robert; Išgum, Ivana; Henriques, José P.; De Vos, Bob D.; Delewi, Ronak

Background: Manual muscle mass assessment based on Computed Tomography (CT) scans is recognized as a good marker for malnutrition, sarcopenia, and adverse outcomes. However, manual muscle mass analysis is cumbersome and time consuming. An accurate fully automated method is needed. In this study, we evaluate …

2022-05AlgemeenArtikel

Psychometric evaluation of the Decision Support Tool for Functional Independence in community-dwelling older people

Sander van Bijsterveld (Onderzoeker); Di-Janne Barten (Onderzoeker); Esther Molenaar (Onderzoeker); Nienke Bleijenberg (Lector); Niek de Wit (Onderzoeker); Cindy Veenhof (Lector)

Background: The aging population is increasingly faced with daily life limitations, threatening their Functional Independence (FI). These limitations extend different life domains and require a broad range of community-care professionals to be addressed. The Decision Support Tool for Functional Independence …

2022GezondheidArtikel

Validatie van de smartphone applicatie D’angle bij gezonde individuen

Dennis van der Linde (Student)

Het objectiveren van de bewegingsuitslag (ROM) in gewrichten is een belangrijk onderdeel binnen de fysiotherapie. Het meest gebruikte valide meetinstrument, de goniometer, is onhandig in het gebruik waardoor vaak gekozen wordt voor een visuele inschatting welke erg onbetrouwbaar is. Smartphones nemen …

2021-06-11GezondheidBachelor

Betrouwbaarheid en validiteit van het testen van het uithoudingsvermogen bij mensen met een unilaterale amputatie aan de onderste extremiteit

Gerrita Dasselaar (Student); Martin Brouwer (Begeleider)

Wereldwijd vinden jaarlijks zes tot 31 beenamputaties plaats per 100.000 mensen, in de toekomst zal dit naar alle waarschijnlijkheid toenemen. Het uithoudingsvermogen is een belangrijke indicator of mensen met een amputatie uiteindelijk met een prothese gaan lopen, omdat het lopen met een prothese meer …

2021-06-04GezondheidBachelor

Agreement Between the KTK3+ Test and the Athletic Skills Track for Classifying the Fundamental Movement Skills Proficiency of 6- to 12-Year-Old Children

Mark de Niet (Onderzoeker); Sebastiaan Platvoet (Onderzoeker); J.J.A.A.M. Hoeboer (Lid Lectoraat); A.M.H de Witte (Lid Lectoraat); S.I. de Vries (Lector); J. Pion (Onderzoeker)

The main aim of this study was to determine the agreement in classification between the modified KörperKoordinations Test für Kinder (KTK3+) and the Athletic Skills Track (AST) for measuring fundamental movement skill levels (FMS) in 6- to 12-year old children. 3,107 Dutch children (of which 1,625 are …

2021-03-10GezondheidArtikel

Translation, adaptation, validity and reliability of the Dutch version of the 'blue flags' questionnaire

A Westerweel; Yvonne Heerkens; Wiebke Oswald; CP Sennehed; K. Stigmar; Suzanne van Hees; Wim van Lankveld; Nathan Hutting

Purpose: To translate and culturally adapt the Swedish version of the 'Blue flags' questionnaire into Dutch and to examine the validity and reliability aspects of the Dutch version. Methods: The 'Blue flags' questionnaire was translated and culturally adapted to the Dutch situation. A total of 58 participants …

2021AlgemeenArtikel

Test-retest reliability and concurrent validity of the Adapted Short QUestionnaire to ASsess Health-enhancing physical activity (Adapted-SQUASH) in adults with disabilities

Seves, Bregje L; Hoekstra, Femke; Schoenmakers, Jorrit W A; Brandenbarg, Pim; Hoekstra, Trynke; Hettinga, Florentina J; Dekker, Rienk; van der Woude, Lucas H.V.; van der Schans, Cees P. (Healthy Ageing, Allied Health Care And Nursing)

The current study determined the test-retest reliability and concurrent validity of the Adapted Short QUestionnaire to ASsess Health-enhancing physical activity (Adapted-SQUASH) in adults with disabilities. Before filling in the Adapted-SQUASH twice with a recall period of 2 weeks, participants wore …

2021AlgemeenArtikel

Coexistence of malnutrition, frailty, physical frailty and disability in patients with COPD starting a pulmonary rehabilitation program

ter Beek, L.; van der Vaart, H.; Wempe, J.B.; Krijnen, W.P. (Statistical Techniques For Applied Research); Roodenburg, J.L.N.; van der Schans, C.P. (Healthy Ageing, Allied Health Care And Nursing); Jager-Wittenaar, H. (Malnutrition And Healthy Ageing)

Background & aims: Malnutrition, frailty, physical frailty, and disability are common conditions in patients with chronic obstructive pulmonary disease (COPD). Insight in the coexistence and relations between these conditions may provide information on the nature of the relationship between malnutrition …

2020-08-01AlgemeenArtikel

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