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Zocht je misschien: patients, patienten?

Smartphone-assisted training with education for patients with hip and/or knee osteoarthritis (SmArt-E)

Franziska Weber (Onderzoeker); Carsten Müller (Onderzoeker); Carolin Bahns (Onderzoeker); Christian Kopkow (Onderzoeker); Francesca Färber (Onderzoeker); Paul Gellert (Onderzoeker); Ina Otte (Onderzoeker); Horst Christian Vollmar (Onderzoeker); Werner Brannath (Onderzoeker); Freya Diederich (Onderzoeker); Stephan Kloep (Onderzoeker); Heinz Rothgang (Onderzoeker); Valerie Dieter (Onderzoeker); Inga Krauß (Onderzoeker); Corelien Kloek (Onderzoeker); Cindy Veenhof (Lector); Sandra Collisi (Onderzoeker); Ute Repschläger (Onderzoeker); Hannes Böbinger (Onderzoeker); Christian Grüneberg (Onderzoeker); Christian Thiel (Onderzoeker); Dirk Peschke (Onderzoeker)

Introduction: Hip and knee osteoarthritis are associated with functional limitations, pain and restrictions in quality of life and the ability to work. Furthermore, with growing prevalence, osteoarthritis is increasingly causing (in)direct costs. Guidelines recommend exercise therapy and education as …

2023GezondheidArtikel

Evidence for effect of l-serine, a novel therapy for GRIN2B-related neurodevelopmental disorder.

B. den Hollander; A.R.J. Veenvliet; Marieke Lindenschot; P. van Essen; G. Peters; A. Santos-Gómez; M. Olivella; X. Altafaj; M.M. Brands; B.A.W. Jacobs; C.D. van Karnebeek

RATIONALE: To date, causal therapy is potentially available for GRIN2B-related neurodevelopmental disorder (NDD) due to loss-of-function (LoF) variants in GRIN2B, resulting in dysfunction of the GluN2B subunit-containing N-methyl-d-aspartate receptor (NMDAR). Recently, in vitro experiments showed that …

2023AlgemeenArtikel

Personalized surveillance and aftercare for non-metastasized breast cancer

A. Klaassen‑Dekker; C.H.C. Drossaert; M.C. van Maaren; A.E. van Leeuwen‑Stok; V.P. Retel; J.C. (Joke) Korevaar (Lector); S. Siesling

Background: Follow‑up of curatively treated primary breast cancer patients consists of surveillance and aftercare and is currently mostly the same for all patients. A more personalized approach, based on patients’ individual risk of recurrence and personal needs and preferences, may reduce patient burden …

2023GezondheidArtikel

Activating Relatives to Get Involved in Care After Surgery: Protocol for a Prospective Cohort Study

Musters, Selma C W; Kreca, Sani; van Dieren, Susan; van der Wal-Huisman, Hanneke; Romijn, Johannes A; Chaboyer, Wendy; Nieveen van Dijkum, Els J M; Eskes, Anne M (Lectoraat Patiënt- En Familieparticipatie In De Klinische Zorg)

Background: Postoperative complications and readmissions to hospital are factors known to negatively influence the short- and long-term quality of life of patients with gastrointestinal cancer. Active family involvement in activities, such as fundamental care activities, has the potential to improve …

2023AlgemeenArtikel

Translating Evidence from Dutch Exercise Oncology Trials in Patients with Breast Cancer into Clinical Practice Using the RE-AIM Framework

Ten Tusscher, Marieke R.; Stuiver, Martijn M. (Lectoraat Functioneel Herstel Bij Kanker); Kampshoff, Caroline S.; Huijsmans, Rosalie J.; Aaronson, Neil K.; Velthuis, Miranda; Gal, Roxanne; Van Waart, Hanna; May, Anne M.; Buffart, Laurien M.

Purpose. We aimed to evaluate the potential for implementing exercise interventions for patients with breast cancer in the Netherlands, based on findings of the Dutch randomized controlled trials in this population. Methods. We evaluated the implementation of four Dutch exercise trials retrospectively, …

2023AlgemeenArtikel

The impact of high versus standard enteral protein provision on functional recovery following intensive care admission (PRECISE trial)

van Gassel, Rob J. J.; Bels, Julia L. M.; Tartaglia, Katrien; van Bussel, Bas C. T.; van Kuijk, Sander M. J.; Deane, Adam M.; Puthucheary, Zudin; Weijs, Peter J. M. (Lectoraat Voeding En Beweging); Vloet, Lilian; Beishuizen, Bert; De Bie Dekker, Ashley; Fraipont, Vincent; Lamote, Stoffel; Ledoux, Didier; Scheeren, Clarissa; De Waele, Elisabeth; van Zanten, Arthur R. H.; Mesotten, Dieter; van de Poll, Marcel C. G.

Background Critically ill patients are subject to severe skeletal muscle wasting during intensive care unit (ICU) stay, resulting in impaired short- and long-term functional outcomes and health-related quality of life. Increased protein provision may improve functional outcomes in ICU patients by attenuating …

2023AlgemeenArtikel

Effect of lung ultrasound-guided fluid deresuscitation on duration of ventilation in intensive care unit patients (CONFIDENCE)

Blok, Siebe G.; Mousa, Amne; Brouwer, Michelle G.; de Grooth, Harm-Jan; Neto, Ary Serpa; Blans, Michiel J.; den Boer, Sylvia; Dormans, Tom; Endeman, Henrik; Roeleveld, Timo; Scholten, Harm; van Slobbe-Bijlsma, Eline R.; Scholten, Erik; Touw, Hugo; van der Ven, Fleur Stefanie L. I. M.; Wils, Evert-Jan; van Westerloo, David J.; Heunks, Leo M. A.; Schultz, Marcus J.; Paulus, Frederique (Lectoraat Critical Care); Tuinman, Pieter R.

Background Fluid therapy is a common intervention in critically ill patients. It is increasingly recognised that deresuscitation is an essential part of fluid therapy and delayed deresuscitation is associated with longer invasive ventilation and length of intensive care unit (ICU) stay. However, optimal …

2023AlgemeenArtikel

Effect of physical exercise on the hippocampus and global grey matter volume in breast cancer patients

Koevoets, E.W.; Geerlings, M.I.; Monninkhof, E.M.; Mandl, R.; Witlox, L.; van der Wall, E.; Stuiver, M.M. (Lectoraat Functioneel Herstel Bij Kanker); Sonke, G.S.; Velthuis, M.J.; Jobsen, J.J.; van der Palen, J.; Bos, M.E.M.M.; Göker, E.; Menke-Pluijmers, M.B.E.; Sommeijer, D.W.; May, A.M.; de Ruiter, M.B.; Schagen, S.B.

Background Physical exercise in cancer patients is a promising intervention to improve cognition and increase brain volume, including hippocampal volume. We investigated whether a 6-month exercise intervention primarily impacts total hippocampal volume and additionally hippocampal subfield volumes, cortical …

2023AlgemeenArtikel

Physical, social, mental and spiritual functioning of COVID-19 intensive care unit-survivors and their family members one year after intensive care unit-discharge

Onrust, Marisa; Visser, Anja; van Veenendaal, Nadine; Dieperink, Willem; Luttik, Marie Louise (Family Care); Derksen, Mechteld-Hanna G.; van der Voort, Peter H. J.; van der Meulen, Ingeborg C.

OBJECTIVE: To describe the long-term functioning of patients who survived a COVID-19-related admission to the intensive care unit and their family members, in the physical, social, mental and spiritual domain. DESIGN: A single-centre, prospective cohort study with a mixed-methods design. SETTING: The …

2022-12-07AlgemeenArtikel

Subjective Mouthfeel and Temperature Alterations in COVID-19 Patients Six to Ten Months After Diagnosis

van Elst, Jip M; Boesveldt, Sanne; Vissink, Arjan; Jager-Wittenaar, Harriët (Malnutrition And Healthy Ageing); Reyners, Anna K L; de Haan, Jacco J

INTRODUCTION: The characteristics and impact of mouthfeel, temperature, smell, and taste alterations in patients with COVID-19 at a long term are yet not well known. In this study, these characteristics and their impact on daily life and quality of life (QoL) were assessed, six to ten months after infection, …

2022-10-01AlgemeenArtikel

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