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Supercritical fluid extraction of oil from Andean Lupin seeds

Yu, Miao (Biorefinery); Kniepkamp, Kai (Biorefinery); Kulchenko, Yaroslava; Witkamp, Geert-Jan; van Haren, R.J.F. (Biorefinery)

2019-01-29AlgemeenConferentiebijdrage

Plasma citrulline concentration, a marker for intestinal functionality, reflects exercise intensity in healthy young men

Shirley Kartaram (Lid Lectoraat); Marco Mensink; Marc Teunis (Lid Lectoraat); Eric Schoen; Lonneke Janssen - Duijghuijsen; Martie Verschuren; Karin Mohrmann; Laura M'Rabet (Lid Lectoraat); Karen Knipping; Harriët Wittink (Lector); Andy van Helvoort; Johan Garssen; Renger Witkamp; Raymond Pieters (Lector); Klaske van Norren

Background & aims Plasma citrulline concentration is considered to be a marker for enterocyte metabolic mass and to reflect its reduction as may occur during intestinal dysfunction. Strenuous exercise can act as a stressor to induce small intestinal injury. Our previous studies suggest that this comprises …

2019GezondheidArtikel

Release of major peanut allergens from their matrix under various pH and simulated saliva conditions—Ara h2 and ara h6 are readily bio-accessible

Stef J. Koppelman (Onderzoeker); Mieke Smits (Lid Lectoraat); Monic Tomassen (Onderzoeker); Govardus A.H. de de Jong (Onderzoeker); Joe Baumert (Onderzoeker); Steve L. Taylor (Onderzoeker); Renger Witkamp (Onderzoeker); Robert Jan Veldman (Lid Lectoraat); Raymond Pieters (Lector); Harry Wichers (Onderzoeker)

from the article: "Abstract: The oral mucosa is the first immune tissue that encounters allergens upon ingestion of food. We hypothesized that the bio-accessibility of allergens at this stage may be a key determinant for sensitization. Light roasted peanut flour was suspended at various pH in buffers …

2018-09-11GezondheidArtikel

Aard en omvang ouderenmishandeling

Janine Janssen; Jolanda Lindenberg; Leonie Bakker; Bertine Witkamp; Maartje Timmermans; Anne Werter; Remy Boerhoop; Mats Gorter

Voorliggend rapport biedt op basis van verschillende perspectieven zicht op de aard en omvang van ouderenmishandeling bij thuiswonende 65-plussers in Nederland. Actuele kennis over deze problematiek is in een vergrijzende samenleving als de onze van groot belang om meer grip te krijgen op het probleem …

2018-05-25Mens & MaatschappijRapport

Nutritional Supplement Use by Dutch Elite and Sub-Elite Athletes: Does Receiving Dietary Counseling Make a Difference?

F.C. Wardenaar; Ingrid Ceelen; Jan-Willem van Dijk; R.W. Hangelbroek; L. Van Roy; B. Van der Pouw; JHM de Vries; M. Mensink; R.F. Witkamp

The use of nutritional supplements is highly prevalent among athletes. In this cross-sectional study, we assessed the prevalence of nutritional supplement use by a large group of Dutch competitive athletes in relation to dietary counseling. A total of 778 athletes (407 males and 371 females) completed …

2017AlgemeenArtikel

N-Docosahexaenoyl Dopamine, an Endocannabinoid-like Conjugate of Dopamine and the n-3 Fatty Acid Docosahexaenoic Acid, Attenuates Lipopolysaccharide-Induced Activation of Microglia and Macrophages via COX-2

YA Wang (Onderzoeker); P. Plastina (Onderzoeker); Jean-Paul Vincken (Onderzoeker); Renate Jansen (Onderzoeker); Michiel Balvers (Onderzoeker); Jean Paul ten Klooster (Lid Lectoraat); Harry Gruppen (Onderzoeker); Renger Witkamp (Onderzoeker); Jocelijn Meijerink (Onderzoeker)

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.6b00298 From teh publisher: "Several studies indicate that the n-3 long-chain polyunsaturated fatty acid docosahexaenoic acid (DHA) contributes to an attenuated inflammatory status in the development of neurodegenerative disorders, such as Alzheimer’s …

2017GezondheidArtikel

Docosahexaenoyl Serotonin, an endogenously formed n-3 fatty acid-serotonin conjugate has anti-inflammatory properties by attenuating IL-23–IL-17 signalling in macrophages

Jean Paul ten Klooster (Lid Lectoraat); Raymond Pieters (Lector); Mieke Polanda; Zheng Wang; Renger Witkamp; Jocelijn Meijerink; Mark Boekschoten

Abstract from the article: "Conjugates of fatty acids and amines, including endocannabinoids, are known to play important roles as endogenous signaling molecules. Among these, the ethanolamine conjugate of the n-3 poly unsaturated long chain fatty acid (PUFA) docosahexaenoic acid (22:6n-3) (DHA) was …

2016-09-26Gezondheid; …Artikel

How to Deal With Relatives of Patients Dying in the Hospital? Qualitative Content Analysis of Relatives’ Experiences

R. Janssens; M. Droger; L. van Zuylen; A. van der Heide; F.E. Witkamp (Lid Lectoraat)

Hospital care and communication tend to be focused on the individual patient, and decision making is typically based on the principle of individual autonomy. It can be questioned whether this approach is adequate when a patient is terminally ill.

2016-08-01GezondheidArtikel

Tot de Kern Eindrapportage

C.M. Dekker - van Doorn (Lector); A.L. van Staa (Lector); C.V.M. Vahedi Nikbakht - van de Sande; F.E. Witkamp (Docent)

Stichting Fibula had, een jaar na uitgave van de Handreiking minimale eisen netwerken palliatieve zorg de wens om een eerste indruk te krijgen van de mate waarin de vier kerntaken van de NPZ nu reeds geborgd zijn in het veld. Ook wilde ze weten hoe de netwerken invulling geven aan regionaal maatwerk …

2016-05-03GezondheidRapport

The effect of endurance exercise on intestinal integrity in well‐trained healthy men

Lonneke Janssen - Duijghuijsen; Marco Mensink; Kaatje Lenaerts; Ewa Fiedorowicz; Dorien van Dartel; Jurriaan Mes; Yvette Luiking; Harry Wichers; Renger Witkamp; Klaske van Norren; Shirley Kartaram (Lid Lectoraat); Anne Geijsen; Astrid van der Harst; Martie Verschuren; Leon Knippels; Raymond Pieters (Lector)

Exercise is one of the external factors associated with impairment of intestinal integrity, possibly leading to increased permeability and altered absorption. Here, we aimed to examine to what extent endurance exercise in the glycogen‐depleted state can affect intestinal permeability toward small molecules …

2016GezondheidArtikel

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