Inhibition of the sodium–glucose cotransporter 2 (SGLT2) by canagliflozin in type 2 diabetes mellitus results in large between-patient variability in clinical response. To better understand this variability, the positron emission tomography (PET) tracer [18F]canagliflozin was developed via a Cu-mediated …

Inhibition of the sodium−glucose cotransporter 2 (SGLT2) by canagliflozin in type 2 diabetes mellitus results in large between-patient variability in clinical response. To better understand this variability, the positron emission tomography (PET) tracer [18F]canagliflozin was developed via a Cu-mediated …

BACKGROUND: Differentiating dementia from baseline level of functioning is difficult among people with severe/profound intellectual (and multiple) disabilities. Moreover, studies on observable dementia symptoms are scarce. This study examined (a) the relevance of dementia diagnosis, (b) observable symptoms …

This paper aims to quantify the evolution of damage in masonry walls under induced seismicity. A damage index equation, which is a function of the evolution of shear slippage and opening of the mortar joints, as well as of the drift ratio of masonry walls, was proposed herein. Initially, a dataset of …

Purpose: The aim of this brief review was to present an overview of noninvasive markers in trained to professional endurance athletes that can reflect a state of functional overreaching. Methods: A systematic literature search was conducted in the PubMed, Scopus, and PsycINFO databases. After screening …

The rise of financial technology (fintech) driven business models in banking poses a challenge for financial regulators. While the positive effects on the banking sector in terms of greater diversity and competition are generally recognized and encouraged by regulators, the nature of fintech business …

Airway care interventions may prevent accumulation of airway secretions and promote their evacuation, but evidence is scarce. Interventions include heated humidification, nebulization of mucolytics and/or bronchodilators, manual hyperinflation and use of mechanical insufflation-exsufflation (MI-E). Our …

Funding Acknowledgements Type of funding sources: None. Background An important factor related to low physical activity in cardiac patients is fear of movement (kinesiophobia). The setting of cardiac rehabilitation (CR) seems suitable for targeting kinesiophobia. Nevertheless, the impact of CR on kinesiophobia …

During the 2015 Gorkha earthquake of 7.8 Mw that hit Kathmandu Valley, Nepal, numerous Nepalese Pagodas suffered extensive damage while others collapsed. Risk reduction strategies implemented in the region focused on disassembling historical structures and rebuilding them with modern material without …

OBJECTIVES: The aim of this study was to evaluate the association between integrated care and health-related quality of life (HRQOL) in a primary care practice population. DESIGN: A cross-sectional survey study. SETTING: Primary care practice population. PARTICIPANTS: A sample (n=5562) of patients in …