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Differential Pneumococcal Growth Features in Severe Invasive Disease Manifestations

Arends, Daan W.; Alkema, Wynand; Hapsari Putri, Indri; van der Gaast–de Jongh, Christa E.; Eleveld, Marc; Langereis, Jeroen D.; de Mast, Quirijn; Meis, Jacques F.; de Jonge, Marien I.; Cremers, Amelieke J. H.

The nasopharyngeal commensal Streptococcus pneumoniae can become invasive and cause metastatic infection. This requires the pneumococcus to have the ability to adapt, grow, and reside in diverse host environments. Therefore, we studied whether the likelihood of severe disease manifestations was related …

2022-06-09AlgemeenArtikel

Sputum Proteome Signatures of Mechanically Ventilated Intensive Care Unit Patients Distinguish Samples with or without Anti-pneumococcal Activity

Seinen, Jolien; Engelke, Rudolf; Abdullah, Mohammed R; Voß, Franziska; Michalik, Stephan; Dhople, Vishnu M; Dieperink, Willem; de Smet, Anne Marie G A; Völker, Uwe; van Dijl, Jan Maarten; Schmidt, Frank; Hammerschmidt, Sven

Respiratory pathogens like Streptococcus pneumoniae can cause severe pneumonia. Nonetheless, mechanically ventilated intensive care patients, who have a high risk of contracting pneumonia, rarely develop pneumococcal pneumonia. Mechanically ventilated patients are at risk of contracting pneumonia. Therefore, …

2021-04-27AlgemeenArtikel

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Differential Pneumococcal Growth Features in Severe Invasive Disease Manifestations

Sputum Proteome Signatures of Mechanically Ventilated Intensive Care Unit Patients Distinguish Samples with or without Anti-pneumococcal Activity

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