Background: As populations age, maintaining physical activity (PA) is essential to reduce chronic disease risk and preserve functional independence in older adults. Technology-supported interventions, such as wearables, mobile applications, and web-based platforms, have emerged as effective tools to …

Clinical outcomes in ROS1-fusion positive (ROS1+) non-small cell lung cancer (NSCLC) by fusion partner and resistance mechanisms are limited. This cohort study included 56 ROS1+ patients (FISH or NGS confirmed); fusion partners were identified in 27 cases, including CD74 (n = 10), EZR (n = 7), and SDC4 …

The high prevalence rate of tobacco consumption among teenage school students has become a global issue with profound implications for their developmental trajectory. Research conducted at drug-abuse hot-spots as a proximal factor related to tobacco use has been limited. Therefore, the present study …

Background Families with intellectual disabilities are overrepresented in child protection systems. However, little is known about how adverse experiences co-occur in this population. This study examined the prevalence and interrelations of original and extended adverse childhood experiences (ACEs) and …

Factors associated with physical activity among patients eligible for cardiac rehabilitation: a qualitative studyTo optimize recovery following a cardiac event, Cardiac Rehabilitation (CR) is often recommended. Currently, CR is mostly offered as a standardized program, consisting of exercise therapy, …

Emergency medical service nurses worldwide face continuous high-stress situations caused by critical incidents that can overwhelm them emotionally and affect their daily functioning and sustainable employability. Repeated exposure to these incidents negatively impacts their mental health. The COVID-19 …

This dissertation describes the dynamics of motor competence (MC) development from early childhood (EC) to middle childhood (MCD). Being motor competent in early childhood creates a window of opportunity for taking part in physical activities later in childhood and adulthood. However, there is a worrying …

Obesity is a growing global burden with numerous significant health implications, including a higher risk of developing Alzheimer’s disease (AD). This study investigates the role of obese adipose tissue on AD pathology in male APPswe/PSEN1-dE9 (APP/PSEN-1) transgenic mice, with a focus on cognitive decline, …

Due to environmental protection efforts, there is a growing number of beavers in the Netherlands. As these animals make their burrows in the levee system they cause damage within it, increasing the risk of flooding. This paper assesses the factors which increase the risk of beaver activity within the …

Surviving a burn can dramatically alter a child’s life, yet few studies examined long-term health-related quality of life (HRQL). This study assessed HRQL 5–7 years post-burn in children with mild/intermediate and severe burns and identified associated factors. Parents of children (5− < 18 years) who …