This commentary is on the original article by Whitney and Basu. To view this paper visit https://doi.org/10.1111/dmcn.14879

Background: Hypothyroidism is a common endocrine disorder and the standard treatment is replacement therapy with levothyroxine (LT4). Although many hypothyroid patients improve upon treatment with LT4, a proportion seems to experience residual hypothyroid complaints despite treatment, even when plasma …