HBO Kennisbank

3 Resultaten

Sorteer op:

Zocht je misschien: lymphocytes?

Complete remission and long-term survival of a patient with a diffuse large B-cell lymphoma under Viscum album extracts after resistance to R-CHOP

Erik Baars (Lector); Johannes Gutsch (Onderzoeker); Paul G. Werthmann (Onderzoeker); Andreas Rosenwald (Onderzoeker); Gunver S. Kienle (Onderzoeker)

Background: A nodular lymphocyte predominant Hodgkin's lymphoma (NLPHL) is a lymphoproliferative neoplasm with a fair prognosis, but the possibility of a malignant transformation into a diffuse large B-cell lymphoma (DLBCL) is high. DLBCL progresses aggressively. Introduction of rituximab into therapy …

2018-07-24GezondheidArtikel

Molecular pathway profiling of T lymphocyte signal transduction pathways; Th1 and Th2 genomic fingerprints are defined by TCR and CD28-mediated signaling

Smeets, Ruben L; Fleuren, Wilco W M; He, Xuehui; Vink, Paul M; Wijnands, Frank; Gorecka, Monika; Klop, Henri; Bauerschmidt, Sussane; Garritsen, Anja; Koenen, Hans J P M; Joosten, Irma; Boots, Annemieke M H; Alkema, Wynand (Data Science For Life Science & Health)

BACKGROUND: T lymphocytes are orchestrators of adaptive immunity. Naïve T cells may differentiate into Th1, Th2, Th17 or iTreg phenotypes, depending on environmental co-stimulatory signals. To identify genes and pathways involved in differentiation of Jurkat T cells towards Th1 and Th2 subtypes we performed …

2012-03-14AlgemeenArtikel

Prednisolone-induced changes in gene-expression profiles in healthy volunteers

Toonen, Erik J M; Fleuren, Wilco W M; Nässander, Ulla; van Lierop, Marie-José C; Bauerschmidt, Susanne; Dokter, Wim H A; Alkema, Wynand (Data Science For Life Science & Health)

BACKGROUND: Prednisolone and other glucocorticoids (GCs) are potent anti-inflammatory and immunosuppressive drugs. However, prolonged use at a medium or high dose is hampered by side effects of which the metabolic side effects are most evident. Relatively little is known about their effect on gene-expression …

2011-07-25AlgemeenArtikel

Vorige Volgende

Complete remission and long-term survival of a patient with a diffuse large B-cell lymphoma under Viscum album extracts after resistance to R-CHOP

Molecular pathway profiling of T lymphocyte signal transduction pathways; Th1 and Th2 genomic fingerprints are defined by TCR and CD28-mediated signaling

Prednisolone-induced changes in gene-expression profiles in healthy volunteers

Over HBO Kennisbank