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Intramuscular short-chain acylcarnitines in elderly people are decreased in (pre-)frail females, but not in males

Hoek, M.D. van der; Nieuwenhuizen, A.G.; Kuda, O.; Bos, P.; Paluchová, V.; Verschuren, L. ; Hoek, A.M. van den; Kleemann, R.; Veeger, N.J.G.M. ; Leij, F.R. van der (Lector); Keijer, J.

This study tested the hypothesis that in human aging, a decreased intramuscular acylcarnitine status is associated with (pre-)frailty, reduced physical performance, and altered mitochondrial function. We used a cross-sectional study design with well-matched fit and (pre-)frail old males and females, …

2020-06-15GezondheidArtikel

Intramuscular short-chain acylcarnitines in elderly people are decreased in (pre-)frail females, but not in males.

Marjanne van der Hoek (Onderzoeker); Arie Nieuwenhuizen (Onderzoeker); Ondřej Kuda (Onderzoeker); Paul Bos (Onderzoeker); Veronika Paluchová (Onderzoeker); Lars Verschuren (Onderzoeker); Anita van den Hoek (Onderzoeker); Robert Kleemann (Onderzoeker); Nic Veeger (Onderzoeker); Feike van der Leij (Lector); Jaap Keijer (Onderzoeker)

We tested the hypothesis that in human ageing a decreased intramuscular acylcarnitine status is associated with (pre-)frailty, reduced physical performance and altered mitochondrial function. Results showed that intramuscular total carnitine levels and acetylcarnitine levels were lower in (pre-)frail …

2020-06-15GezondheidArtikel

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Intramuscular short-chain acylcarnitines in elderly people are decreased in (pre-)frail females, but not in males

Intramuscular short-chain acylcarnitines in elderly people are decreased in (pre-)frail females, but not in males.

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