Background This research study applied the 'Integrated Energy Landscape Approach and the Ecosystem Services Framework' to formulate a pre-proposal for a Positive Energy District in the Hoogkerk Zuid neighborhood in Groningen, the Netherlands. Results The proposed energy saving and energy generation interventions …

Citizen science can be a powerful approach to foster the successful implementation of technological innovations in health, care or well-being. Involving experience experts as co-researchers or co-designers of technological innovations facilitates mutual learning, community building, and empowerment. …

This project challenges traditional cognition-based research methods. While informative, they do not fully capture the complexity of economic transformation. This hinders our ability to support regenerative entrepreneurs in their journey toward a fair and sustainable economy. At AUAS Centre for Economic …

The first Stakeholder Network Meeting of the EU Horizon 2020-funded ONTOX project was held on 13-14 March 2023, in Brussels, Belgium. The discussion centred around identifying specific challenges, barriers and drivers in relation to the implementation of non-animal new approach methodologies (NAMs) and …

Both because of the shortcomings of existing risk assessment methodologies, as well as newly available tools to predict hazard and risk with machine learning approaches, there has been an emerging emphasis on probabilistic risk assessment. Increasingly sophisticated AI models can be applied to a plethora …

While the original definition of replacement focuses on the replacement of the use of animals in science, a more contemporary definition focuses on accelerating the development and use of predictive and robust models, based on the latest science and technologies, to address scientific questions without …

New approach methodologies predicting human cardiotoxicity are of interest to support or even replace in vivo-based drug safety testing. The present study presents an in vitro–in silico approach to predict the effect of inter-individual and inter-ethnic kinetic variations in the cardiotoxicity of R- …

Adverse Outcome Pathways (AOPs) are conceptual frameworks that tie an initial perturbation (molecular initiat- ing event) to a phenotypic toxicological manifestation (adverse outcome), through a series of steps (key events). They provide therefore a standardized way to map and organize toxicological …

Many countries experience waning public trust in government, while digitisation of society is on the rise and public authorities continue to further digitise their services. If governments do not pay enough attention to the perspective of citizens and adopt a citizen-centric approach while designing …

Purpose: The study aims to explain the communicative basis of conflicts in which actors stand in opposition in defining a negotiated situation and to deepen knowledge of environmental conflict development, in particular on how frames are (re)shaped through discursive choices in interaction. Design/methodology/approach: This …