The growing prevalence of AI systems in society, has also prompted a growth of AI systems in the public sector. There are however ethical concerns over the impact of AI on society and how this technology can impact public values. Previous works do not connect public values and the development of AI. …

To study the ways in which compounds can induce adverse effects, toxicologists have been constructing Adverse Outcome Pathways (AOPs). An AOP can be considered as a pragmatic tool to capture and visualize mechanisms underlying different types of toxicity inflicted by any kind of stressor, and describes …

Comprehensive understanding of the merits of bottom-up urban development is lacking, thus hampering and complicating associated collaborative processes. Therefore, and given the assumed relevancies, we mapped the social, environmental and economic values generated by bottom-up developments in two Dutch …

To successfully develop a system, a solid understanding of its architecture by stakeholders involved in the development of the system is key. This process is supported by System Architects, who have a profession that is often regarded as experience based. However, we argue that it is important to familiarize …

Summary: Xpaths is a collection of algorithms that allow for the prediction of compound-induced molecular mechanisms of action by integrating phenotypic endpoints of different species; and proposes follow-up tests for model organisms to validate these pathway predictions. The Xpaths algorithms are applied …

Het boek ‘Create Health Ways of Working: Insights from ten eHealth innovation research projects’ presenteert inzichten uit het meta-onderzoeksproject ‘Create & Health Innovation WAys of Working Analysis’, ook wel CHIWAWA genoemd. Binnen dit meta-onderzoeksproject inventariseerden onderzoekers van de …

This study explores the evaluation of research pathways of self-management health innovations from discovery to implementation in the context of practice-based research. The aim is to understand how a new process model for evaluating practice-based research provides insights into the implementation success …

Abstract Background One of the most problematic expression of ageing is frailty, and an approach based on its early identification is mandatory. The Sunfrail-tool (ST), a 9-item questionnaire, is a promising instrument for screening frailty. Aims • To assess the diagnostic accuracy and the construct …

The European Union is implementing policies to achieve its priorities of the European Green Deal; A Europe fit for the digital age; An economy that works for people; and A stronger Europe in the world. To achieve these goals, there is a need for a paradigm shift in the way public and private sector organisations, …

This study explores the evaluation of research pathways of self-management health innovations from discovery to implementation in the context of practice-based research. The aim is to understand how a new process model for evaluating practice-based research provides insights into the implementation success …