Background The ROS1 G2032R mutation is the most common on-target resistance mutation in crizotinib treated ROS1-positive lung cancer patients. The aim of our study was to investigate resistance mechanisms in SCL34A2-ROS1G2032R positive Ba/F3 cells against second line treatment with lorlatinib. Methods …

DNA barcoding is an important molecular methodology for species identification that was developed over the last two decades and it should be covered inthe biology bachelor curriculum. Here, we present an example of DNA barcoding by sequencing a segment of the 28S nuclear ribosomal large subunitrRNA gene …

Bryophytes are small, haploid, non-vascular plants, which can be divided in three distinct phyla; the mosses (Musci), the liverworts (Hepaticae) and the hornworts (Anthocerotae) (Gradstein & Melick, 1996), (Touw, Kruijer, & Stech, 2016). They are valuable indicators of environmental chance, due to the …

The fungal species Trichoderma harzianum is widely used as a biological agent in crop protection. To verify the continued presence of this fungus on plant roots manually inoculated with T. harzianum strain T22, a Q-PCR was designed using specific probes for this particular strain. To develop these molecular …