Abstract – Introduction: Depression is a common mental disorder with often persistent consequences. Even after adequate treatment, recovery may be far from optimal. To enhance outcomes, we aimed to identify and synthesize factors that depressed adults themselves perceived as facilitating or hindering …

In recent years, care for people with severe mental illnesses (SMI) has shifted from institutional to recovery-based treatment in which informal caregivers often have an important role. However, their increased involvement has elevated issues such as role strain or burden of care, which indicates that …

BACKGROUND: In geriatric oncology, family members frequently accompany patients during medical consultations, providing emotional and practical support while participating in shared decision-making (SDM). Family involvement in SDM can facilitate the decision-making process but also pose challenges for …

Samenvatting Behandelbeslissingen voor oudere oncologie patiënten zijn vaak complex. Dit komt door de grote variatie in achtergrond, comorbiditeiten, functionele capaciteiten en de impact van kankerbehandelingen op zowel de levenskwaliteit als de levensverwachting. In deze context is samen beslissen, …

Clinical outcomes in ROS1-fusion positive (ROS1+) non-small cell lung cancer (NSCLC) by fusion partner and resistance mechanisms are limited. This cohort study included 56 ROS1+ patients (FISH or NGS confirmed); fusion partners were identified in 27 cases, including CD74 (n = 10), EZR (n = 7), and SDC4 …

Aim: Mothers of children with intellectual disabilities are particularly vulnerable to mental distress due to demanding and exhausting caregiving. However, in the Arab world, they are seldom screened for depression because of limited diagnostic resources. Addressing the urgent need for brief and reliable …

Background: In the Netherlands, primary care dietitians are the preferred health care professionals for weight management in patients living with overweight and obesity. A clinically relevant weight loss of ≥5% is associated with positive health outcomes. However, a significant proportion of patients …

Background Families of adolescents with severe behavior problems and an Autism Spectrum Disorder (ASD) level 1 may experience a variety of problems in their functioning. Research suggests that these problems across multiple life areas are best treated with intensive, flexible, and home-based treatment …

Post-traumatic stress disorder (PTSD) in later life poses a substantial burden on public health and social care systems. However, research in this population remains scarce. In this Personal View, we review the current state of research on PTSD and ageing, as presented by the On Traumatic Stress and …

Abstract Background There is a shift from inpatient to home-based geriatric rehabilitation (HBGR), and potential benefits are demonstrated. Previously, a theoretical HBGR model, version 1.0, has been developed, outlining its essential components. However, clear guidance on the practical design and organisation …