Abstract: Background: The life expectancy of patients with severe mental illness (SMI) is estimated to be 20 to 30 years shorter than in the general population due to avoidable physical illnesses. This gap is widening. Health care professionals’ performance with regard to physical health and lifestyle …

This thesis provides a report on research aimed at enhancing treatment of patients with bipolar disorder. We describe various aspects of treatment of bipolar disorder. The central study reported in this thesis is an effect study of a multicomponent intervention, Collaborative Care. Chapter 1 describes …

Het Interventieprotocol Zorg in Samenwerking (ZiS) bestaat uit 3 delen: het Achtergronddocument, het Handboek en het Werkboek. In deel I, het Achtergronddocument, worden de theoretische achtergronden van het programma beschreven. Deel II, het Handboek, levert praktische handleidingen en instructies voor …

Bipolar disorder is a severe mental illness with serious consequences for daily living of patients and their caregivers. Care as usual primarily consists of pharmacotherapy and supportive treatment. However, a substantial number of patients show a suboptimal response to treatment and still suffer from …