BACKGROUND: Cervical dystonia (CD) is characterized by involuntary muscle contractions causing abnormal postures and/or twisting movements of the head and neck. These motor symptoms can have a major impact on disability. Treatment with botulinum toxin injections aims to reduce motor symptoms, and therefore …

This thesis provides a report on research aimed at enhancing treatment of patients with bipolar disorder. We describe various aspects of treatment of bipolar disorder. The central study reported in this thesis is an effect study of a multicomponent intervention, Collaborative Care. Chapter 1 describes …

The timely detection of post-stroke depression is complicated by a decreasing length of hospital stay. Therefore, the Post-stroke Depression Prediction Scale was developed and validated. The Post-stroke Depression Prediction Scale is a clinical prediction model for the early identification of stroke …

BACKGROUND: Depression in later life is a common mental disorder with a prevalence rate of between 3% and 35% for minor depression and approximately 2% for Major Depressive Disorder (MDD). The most common treatment modalities for MDD are antidepressant medication and psychological interventions. Recently, …

Research on psychological treatment of depression in inpatients is not conclusive,with some studies finding clear positive effects and other studies finding no significant benefit compared to usual care or structured pharmacotherapy. The results of a meta-analysis investigating how effective psychological …

The study aims to describe the implementation of Activity Scheduling (AS) as a nursing intervention in an inpatient population of older adults with a major depressive disorder. DESIGN AND METHODS:  In a single case report, the implementation of the intervention was described. FINDINGS:  This case report …

What is already known about depression in dementia? Comorbid depression in people with dementia is associated with decreased quality of life (Shin et al., 2005), greater health care utilization (Kunik et al., 2003), higher mortality rates (Suh et al., 2005) and decreased caregiver’s wellbeing (Kerkstra …

Study design: Systematic review Background: The World Health Organisation predicts that depression will create the second greatest burden of diseases by 2020 regarding cost effective prevention and intervention strategies. The evidence to support the benefits of exercise in offering protection from …