Background: The heat shock protein (HSP) inducer, geranylgeranylacetone (GGA), was previously found to protect against atrial fibrillation (AF) remodeling in experimental model systems. Clinical application of GGA in AF is limited, due to low systemic concentrations owing to the hydrophobic character …

In the recent past, the use of resins in modern tread compounds has increased considerably, in order to further improve tire properties. Based on the experience with silica-silane filler system, which led to a different network structure and a significantly changed devulcanization behavior, the influence …

Tires are an important vehicle component, as car handling, safety and fuel economy depend for a major part on the tire composition and construction. As a consequence, tires are improved continuously. The most prominent improvement in the recent past was the use of a silica-silane filler system in passenger …

Using the reversed phase high performance liquid chromatography with diode-array and massspectrometric (in ESI mode) detection, a composition of Catharanthus roseum petals was established. After the acid hydrolysis, all five anthocyanidins were found to be different comparing to the ordinary anthocyanidins …

Coastal tourism and recreation are one of the most rapidly growing fields worldwide and people spend more time outdoors. Skin protection is, in this respect, important to prevent severe skin damage and skin aging. The past decades the awareness and the importance of skin protection against long time …

This paper describes the development of one solid phase extraction method for a wide group of pharmaceutical and industrial compounds in wastewater that is analyzed with two LC-MS/MS methods.

Relatively new products which are mostly marketed by online communities and online influencers as healthy or having therapeutic effects are being sold across Europe and United States, online or local drugstores, without ensuring that these products go through any quality analysis. This introduces a threat …

From the article: "To enable selection of novel chemicals for new processes, there is a recognized need for alternative toxicity screening assays to assess potential risks to man and the environment. For human health hazard assessment these screening assays need to be translational to humans, have …

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The disruption of nutrient cycles caused by human activities such as agriculture and burning fossil fuels is impacting ecosystem services on global and local scales. The increasing concentration of carbon dioxide in the atmosphere contributes to rising global temperatures and ocean acidification, whereas …