Individuals with mild intellectual disabilities or borderline intellectual functioning are at increased risk to develop a substance use disorder—however, effective treatment programs adapted to this target group are scarce. This study evaluated the effectiveness of Take it Personal!+ in individuals with …

RATIONALE: To date, causal therapy is potentially available for GRIN2B-related neurodevelopmental disorder (NDD) due to loss-of-function (LoF) variants in GRIN2B, resulting in dysfunction of the GluN2B subunit-containing N-methyl-d-aspartate receptor (NMDAR). Recently, in vitro experiments showed that …

Insomnia has a negative impact on mental health and is a potential risk factor for impulsive and problematic behavior. This multicenter, cross-sectional study investigated the prevalence of insomnia and underlying and maintaining factors in a group of forensic psychiatric inpatients (N = 281). Insomnia …

Background: The prevalence of Substance Use Disorder (SUD) in people with Mild Intellectual Disability and Borderline Intellectual Functioning (MID-BIF) is high and evidence-based treatment programs are scarce. The present study describes the development of a personalised SUD treatment for people with …

This study investigates the clinical course of and prognostic factors for quality of life (Short Form 36 items Health survey (SF-36)) and global perceived effect (GPE) in patients treated for chronic nonspecific low back pain at 5 and 12-months follow-up. Data from a prospective cohort (n ¼ 1760) of …

ACHTERGROND: ‘Beginnende’ somatisatie komt voor bij 10-35% van de patiënten in de eerste lijn, waarbij de symptomen ‘vermoeidheid’ en ‘pijn’ en een verminderde ‘kwaliteit van leven’ het meest op de voorgrond staan. Tot op heden nemen de klachten bij deze patiënten met 10-30% toe doordat nergens de beste …

‘Wat voel ik?’ is a study about the contribution of psychomotor therapy (PMT) in recognizing emotions by youth with mild intellectual disabilities (MID) in a age of 12 until 20 years. The study should result in a number of clues about how the PMT, as a form of treatment, can be used to learn youth with …

Doel: Literatuuronderzoek naar de meest effectieve fysiotherapeutische interventie (ontspanning, cognitieve gedragstherapie en fysieke training) bij mensen met burn-out gerelateerde klachten (depersonalisatie, emotionele uitputting, verminderde persoonlijke bekwaamheid, angst, hartslag, bloeddruk en …