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The impact of frailty on the use of social services, medication and mortality risk

Kleinenberg-Talsma, Nanda (Healthy Ageing, Allied Health Care And Nursing); van der Lucht, Fons (Healthy Ageing, Allied Health Care And Nursing); Jager-Wittenaar, Harriët (Healthy Ageing, Allied Health Care And Nursing); Krijnen, Wim (Healthy Ageing, Allied Health Care And Nursing); Finnema, Evelyn

Background: Frailty is a common condition in older people, and its prevalence increases with age. With an ageing population, the adverse consequences of frailty cause an increasing appeal to the health care system. The impact of frailty on population level is often assessed using adverse health outcomes, …

2024-10-23AlgemeenArtikel

High protein provision of more than 1.2 g/kg improves muscle mass preservation and mortality in ICU patients

van Ruijven, Isabel M. (Lectoraat Voeding En Beweging); Abma, José; Brunsveld-Reinders, Anja H.; Stapel, Sandra N.; van Etten-Jamaludin, Faridi; Boirie, Yves; Barazzoni, Rocco; Weijs, Peter J.M. (Lectoraat Voeding En Beweging)

Background ICU patients lose muscle mass rapidly and maintenance of muscle mass may contribute to improved survival rates and quality of life. Protein provision may be beneficial for preservation of muscle mass and other clinical outcomes, including survival. Current protein recommendations are expert-based …

2023-12AlgemeenArtikel

Short-term and long-term increased mortality in elderly patients with burn injury

FRAIL group; Dutch Burn Repository group

BACKGROUND: The population of elderly patients with burn injuries is growing. Insight into long-term mortality rates of elderly after burn injury and predictors affecting outcome is limited. This study aimed to provide this information. METHODS: A multicentre observational retrospective cohort study …

2023-01-17AlgemeenArtikel

Optimal Dosing and Timing of High-Dose Corticosteroid Therapy in Hospitalized Patients With COVID-19

Daenen, Katrijn; Huijben, Jilske A; Boyd, Anders; Bos, Lieuwe D J; Stoof, Sara C M; van Willigen, Hugo; Gommers, Diederik A M P J; Moeniralam, Hazra S; den Uil, Corstiaan A; Juffermans, Nicole P; Kant, Merijn; Valkenburg, Abraham J; Pillay, Janesh; van Meenen, David M P; Paulus, Frederique (Lectoraat Critical Care); Schultz, Marcus J; Dalm, Virgil A S H; van Gorp, Eric C M; Schinkel, Janke; Endeman, Henrik

Background: In hospitalized patients with COVID-19, the dosing and timing of corticosteroids vary widely. Low-dose dexamethasone therapy reduces mortality in patients requiring respiratory support, but it remains unclear how to treat patients when this therapy fails. In critically ill patients, high-dose …

2023-01AlgemeenArtikel

Muscle mass, muscle strength and mortality in kidney transplant recipients: results of the TransplantLines Biobank and Cohort Study

van Vliet, Iris; Post, Adrian; Kremer, Daan; Karin, Boslooper-Meulenbelt; van der Veen, Yvonne; de Jong, Margriet F C; Pol, Robert A; Investigators, TransplantLines; Jager-Wittenaar, Harriët (Malnutrition And Healthy Ageing); Navis, Gerjan; Bakker, Stephan J L

BACKGROUND: Survival of kidney transplant recipients (KTR) is low compared with the general population. Low muscle mass and muscle strength may contribute to lower survival, but practical measures of muscle status suitable for routine care have not been evaluated for their association with long-term …

2022-10-06AlgemeenArtikel

Immune monitoring of T cell and NK cell subsets of non-small cell lung cancer patients receiving neoadjuvant treatment with Chemoradiotherapy, Nivolumab, and Ipilimumab

HL Prijs 2022

Non-small cell lung cancer (NSCLC) occurs in approximately 80-85% of all lung cancer patients and has a 5-year overall survival (OS) of only 15-20%. In this study, 29 NSCLC patients received neoadjuvant treatment with Chemoradiotherapy, Nivolumab, and Ipilimumab. This study aimed to investigate the effects …

2022-06-14GezondheidBachelor

The impact of frailty on survival in elderly intensive care patients with COVID-19

COVIP Study Group

Background: The COVID-19 pandemic has led highly developed healthcare systems to the brink of collapse due to the large numbers of patients being admitted into hospitals. One of the potential prognostic indicators in patients with COVID-19 is frailty. The degree of frailty could be used to assist both …

2021-12-01AlgemeenArtikel

Differences in mortality in critically ill elderly patients during the second COVID-19 surge in Europe

COVIP Study Group

BACKGROUND: The primary aim of this study was to assess the outcome of elderly intensive care unit (ICU) patients treated during the spring and autumn COVID-19 surges in Europe. METHODS: This was a prospective European observational study (the COVIP study) in ICU patients aged 70 years and older admitted …

2021-09-23AlgemeenArtikel

The role of time, weather and Google Trends in understanding and predicting web survey response

Qixiang Fang; Joep Burger; Ralph Meijers; Kees van Berkel (Lector)

In the literature about web survey methodology, significant e orts have been made to understand the role of time-invariant factors (e.g. gender, education and marital status) in (non-)response mechanisms. Time-invariant factors alone, however, cannot account for most variations in (non-)responses, especially …

2021-04-10Economie & ManagementArtikel

Effectiveness of water-saving techniques on growth performance of mango (Mangifera Indica L.) seedlings in Mihitsab-Azmati watershed, Rama Area, northern Ethiopia

Petros, W.; Tesfahunegn, G.B.; Berihu, M.; Meinderts, J.H. (Lid Lectoraat)

Even though mango productivity in Ethiopia is low due to moisture stress, there is no report on how such constraint could alleviate using Cocoon water-saving technology. Cocoon is small water reservoir technology which uses for plant growth in dry season. The objectives of this study were to introduce …

2021-01-01Natuur & LandbouwArtikel

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