Microfluidic devices have the potential to adopt more accurate physiological conditions of the human intestine through the use of continuous flow and by producing mechanical stress to the cells. This study evaluated the translocation properties of a microfluidic gut-on-chip device in comparison with …

Background: Although the incidence of HIV/AIDS has decreased globally, it is on the rise in Eastern Europe. The primary mode of HIV transmission in the region is injecting drug use (IDU) due to the smuggling routes of Afghan heroin into Europe, which makes drugs widely available. The widespread sharing …

Background: The pressure in out-of-hours primary care is high due to an increasing demand for care and rising health-care costs. During the daytime, substituting general practitioners (GPs) with nurse practitioners (NPs) shows positive results to contribute to these challenges. However, there is a lack …

Objective: Product Information Leaflets (PILs) are an important source of information for patients on their medication, but may cause confusion and questions. Patients then may seek clarification, for instance from pharmacy technicians. The aim of this study was to explore which questions pharmacy technicians …

Children with acute respiratory or ear infections (RTI/OM) are often unnecessarily prescribed antibiotics. Antibiotic resistance is a major public health problem and antibiotic prescription for RTI/OM should be reduced. Anthroposophic treatment of RTI/OM includes anthroposophic medications, nonmedication …

BACKGROUND: The use of drug round tabards is a widespread intervention that is implemented to reduce the number of interruptions and medication administration errors (MAEs) by nurses; however, evidence for their effectiveness is scarce. PURPOSE: Evaluation of the effect of drug round tabards on the frequency …

Background: general opinion is growing that drug cessation in complex older patients is warranted in certain situations. From a clinical viewpoint, drug cessation seems most warranted in four situations, i.e., falls, delirium, cognitive impairment and end-of-life situations. To date, little information …

In this investigation the effect of a reward system on the internal motivation to play sports is measured in the hostel of Tactus Drug Rehabilitation. The investigation arised from a disappointing attendance at the sports. In the theoretical background several theories and studies are discussed. One …

The contribution of specific psychotropic drugs to fall risk in patients with dementia has not been quantified precisely until now. The authors evaluated the dose‐response relationship between psychotropic drugs and falls in nursing home residents with dementia. Daily drug use and daily falls were recorded …

BACKGROUND: The face is a very frequent site of burn injuries. This multicenter, randomized, controlled trial thus investigates the effectiveness of cerium nitrate-silver sulfadiazine in the treatment of facial burns compared with silver sulfadiazine. METHODS: Adult patients with acute facial burns admitted …