While the original definition of replacement focuses on the replacement of the use of animals in science, a more contemporary definition focuses on accelerating the development and use of predictive and robust models, based on the latest science and technologies, to address scientific questions without …

The search for existing non-animal alternative methods for use in experiments is currently challenging because of the lack of both comprehensive structured databases and balanced keyword-based search strategies to mine unstructured textual databases. In this paper we describe 3Ranker, which is a fast, …

Implementation of reliable methodologies allowing Reduction, Refinement, and Replacement (3Rs) of animal testing is a process that takes several decades and is still not complete. Reliable methods are essential for regulatory hazard assessment of chemicals where differences in test protocol can influence …

De Westergasfabriek ligt op een prachtig terrein in Amsterdam- West, genaamd Westerpark. De Westergasfabriek kent een lange geschiedenis en is een voormalig industrieterrein volledig getransformeerd tot een bruisende, culturele en recreatieve bestemming. De Westergasfabriek van nu bestaat uit een prachtig …

De afstudeeropdracht wordt uitgevoerd in opdracht van de afdeling S&MB (Small & Medium Business) van AfterPay onder leiding van Daniel Ruff. S&MB bedient alle merchants die niet binnen de Top 150 (Key Accounts) vallen. Deze range loopt van “zolderkamerwebshops” die een paar bestellingen per jaar verwerken …

The research is conducted for Nissan Nederland. Since 2017, this company has changed their method of targets engagement. The goal of this change is dividing the method of targets of two car branches of Nissan Nederland, the private market versus the fleet market. The result of this change should help …

From the article: "To enable selection of novel chemicals for new processes, there is a recognized need for alternative toxicity screening assays to assess potential risks to man and the environment. For human health hazard assessment these screening assays need to be translational to humans, have …

This short paper describes a workshop on “Establishing criteria for an independent 3R-index: Access to 3Rs” and the corporate responsibility of industry for the use of animals in testing. 28 August 2014 Prague, at the World Congress on Alternatives Animal Use in the Life Sciences