Hereditary Breast and Ovarian Cancer (HBOC) typically arises from mutations inherited in the germline. BRCA1 and BRCA2 mutaions are predominant contributors to HBOC, accounting for the majority of cases. These mutations are associated with 10% of ovarian cancer cases and 3-5% of breast cancer cases [4]. BRCA1 …

The TOP program is a fully implemented responsive parenting intervention for very preterm born infants. Fidelity monitoring of interventions is important for preserving program adherence, impact outcomes and to make evidence-based adaptations. The aim of this study was to develop a fidelity tool for …

Oil extraction from Andean lupin beans (Lupinus mutabilis SWEET) via supercritical carbon dioxide (scCO2) was studied on both lab scale and pilot scale. On the lab scale, the effect of pressure, solvent-to-feed ratio (S/F), sample particle size and temperature on oil yield were evaluated. The oil quality …

Data reusability has become a distinct characteristic of scientific, commercial, and administrative practices nowadays. However, an unlimited and careless reuse of data may lead to privacy breaches and unfair impacts on individuals and vulnerable groups. Data content adaption is a key aspect of preserving …

Introduction: Patients with cancer receiving radio- or chemotherapy undergo many immunological stressors. Chronic regular exercise has been shown to positively influence the immune system in several populations, while exercise overload may have negative effects. Exercise is currently recommended for …

Most nurse leadership studies have concentrated on a classical, heroic, and hierarchical view of leadership. However, critical leadership studies have argued the need for more insight into leadership in daily nursing practices. Nurses must align their professional standards and opinions on quality of …

Infiltrating pavements are potentially effective climate adaptation measures to counteract arising challenges related to flooding and drought in urban areas. However, they are susceptible to clogging causing premature degradation. As part of the Dutch Delta Plan, Dutch municipalities were encouraged …

Background Encouraging healthy eating behavior and increasing physical activity can improve health, vitality, and quality of life. Individuals and health professionals have specific needs and wishes. Creative technology allows personalization of blended lifestyle programs that support behavior change …

Buildings need to be carefully operated and maintained for optimum health, comfort, energy performance, and utility costs. The increasing use of Machine Learning combined with Big Data in the building services sector has shown the potential to bring energy efficiency and cost-effectiveness. Therefore, …

Behind the thick doors of the club forms a fantasy world. A democratic society for a night, obeying it’s own rules and challenging all that’s considered normal during the day. It’s inhabitants, although undeniably displaying escapist tendencies, explore and challenge themselves in the sanctuary of freedom. …