The thesis project was devoted to a differentiation of different types of cancer cells checking the effectiveness of the novel anti-leukemia chemicals and exploring whether the best anti-leukemia targets also target bone cancers. The research question of this project is as follows: “How leukemia and …

Young talented athletes that mature have an increased injury risk. Human movement scientist Alien van der Sluis studied soccer players of the talent development program of FC Groningen and tennis players of the talented development program of the Royal Dutch Lawn Tennis Federation (KNLTB). The soccer …

Achtergrond Op de dagbehandeling Hematologie van het Radboudumc is beenmergonderzoek een veelvoorkomende procedure. Ondanks lokale verdoving blijft het voor het merendeel van de patiënten een pijnlijke procedure en resulteert dit in angst en een negatieve ervaring. Verpleegkundigen van de dagbehandeling …

Rationale: The number of obese older adults with diabetes type 2 is increasing worldwide. Weight loss treatment in this group seems beneficial for cardio-metabolic and other health outcomes, but it might reduce muscle mass and bone mineral density (BMD). The association between obesity and BMD is controversial, …

OBJECTIVE: To evaluate the influence of abutment geometry on papillary fill in the esthetic zone in a delayed crown protocol. MATERIALS AND METHODS: Twenty-six subjects received two non-adjacent endosseous implants in the esthetic zone. Functional temporary crowns were installed 17-19 weeks later, using …

In deze kwantitatieve fantoomstudie is de invloed van lucht in de darmen op een dual-energy x-ray absorptiometry scan onderzocht. De gehanteerde onderzoeksvraag luidt: In hoeverre heeft de hoeveelheid lucht in de darmen na een (virtuele) coloscopie invloed op de gemeten "bone mineral density" van een …

Het ontwikkelen van 2D animaties voor spellen ligt al eventjes stil. Na de bone animation ontwikkeling is er in het animatieproces niet veel meer verbeterd. Fantazm is op zoek naar versnelling in het ontwikkelproces van 2D animeren in hun games. Er wordt gekeken naar de bestaande tools en hoe deze geoptimaliseerd …

Postmenopausal bone loss leads to millions of fractures annually. Hormonal replacement therapy is prescribed to offset bone loss, but this treatment includes health risks. Another treatment tool, which stimulates bone formation and following reduces fracture risk is strength training. Therefore the aim …

Hematological malignancies and treatment with hematopoietic SCT are known to affect patients’ quality of life. The problem profile and care needs of this patient group need clarification, however. This study aimed to assess distress, problems and care needs after allo- or auto-SCT, and to identify risk …

OBJECTIVE: Evaluate clinical outcome of early cyclic intravenous pamidronate treatment in children with moderate-to-severe osteogenesis imperfecta (OI), commenced before three years of age. METHODS: A retrospective review of 17 patients with moderate-to-severe OI. Development, anthropometry, fracture …